Fermentation characteristics of novel Coriolus versicolor and Lentinus edodes kombucha beverages and immunomodulatory potential of their polysaccharide extracts

Medicinal mushrooms, Coriolus versicolor and Lentinus edodes are extremely attractive as nutraceuticals. Here we used fruiting bodies to prepare novel kombucha beverage. Microbiological, physicochemical chemical properties were monitored for eleven days, while the immunological of polysaccharide extracts determined in peripheral blood mononuclear cell (PBMC) cultures. FTIR analysis showed dominant presence polysaccharides, addition phenols, lipids proteins. C. extract displayed more complex a higher content total phenols flavonoids compared L. extract. The not cytotoxic PBMC vitro up 500 µg/ml, immunomodulatory effects depended on their compositions. most prominent effect was reduction Th2 cytokines IL-10 Based these results, products could be recommended functional beverages or nutraceuticals with potentially beneficial allergies.